Source - MDLinx
Descriptions of fracture healing almost exclusively deal with shaft fractures and they often emphasize endochondral bone formation. In reality, most fractures occur in metaphysealcancellous bone. Apart from a study of vertebral fractures, authors have not found any histological description of cancellous bone healing in humans. The histology suggests that cells in the midst of the marrow respond to the trauma by direct formation of bone, independently of trabecular surfaces.